Karela contains an insulin-like compound called Polypeptide-p or p-insulin which has been shown to control diabetes naturally. These substances either work individually or together to help reduce blood sugar levels. Karela juice is an excellent beverage for diabetics
Karela has positive effect on diabetes, blood pressure, immune system, pneumonia, cancer and infection (5-7). The extract of fruits has protective effect on diabetic kidney disease due to its antioxidant properties.